(Noah Wyle)

Epoch is unique to the series, in that it's his death that opens the show. We visit different aspects of his life through flashbacks, seeing his loves, his losses, and witnessing how he went on to heal all of the people who would become The Poisoned.

After he received the gift of healing from his father on his father's deathbed, Epoch promised that he wouldn't die with the gift inside him -- the result would be nothing short of a human catastrophe. However, as we witness firsthand, Epoch does die alone, and the gift of healing dies out as well, signalling the creation of The Poisoned.